Alexandra, the bridegroom of the Mideraranain Sea, as Egyptian called it, is the second largest city of Egypt. It was at one time the largest city in the ancient world before being eventually overtaken by Rome. Alexandria was founded in c. 331 BC by Alexander the Great. Alexandria grew rapidly to become an important centre of Hellenistic civilization and remained the capital of Ptolemaic Egypt and Roman and Byzantine Egypt for almost 1,000 years, until the Muslim conquest of Egypt in AD 641.